CSIR NET LIFE SCIENCES BOOKS (VOLUME - I)

CSIR NET LIFE SCIENCES BOOKS (VOLUME - I)

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This book is for CSIR JRF NET LIFE SCIENCES and other entrance examinations.

This book will also cater to the need of students preparing for other competitive exams such as ICAR, ICMR, GATE, TIFR, DBT, IISc, JNU, DU, BHU, M.Sc. Indian Civil Services, Indian Forest Services (IFS), Provincial Civil Services (PCS)  etc. Although the book is designed keeping in mind the CSIR- UGC syllabus for Life Sciences, however, the undergraduate and post-graduate students of various universities across the country will also find this book useful.

The book is simple and has been designed as per the latest syllabus. For the ease of understanding the book is organized into 13 chapters within IV volumes. This book, the volume I of the series concentrates on the first three units of the syllabus, namely UNIT - I: Molecules and their Interaction Relevant to Biology, UNIT - I: Cellular Organization, and UNIT - I: Fundamental Processes.

The content of the volumes are:

 LIFE SCIENCES (Gateway to Success), VOLUME - I

UNIT - I:

MOLECULES AND THEIR INTERACTION RELEVANT TO BIOLOGY 1- 175
A: Structure of atoms, molecules and chemical bonds: 1 - 5
B: Composition, structure and function of biomolecules  (carbohydrates, lipids, proteins, nucleic acids and vitamins): 6 – 68
C: Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding,
hydrophobic interaction, etc.): 69 – 71
D: Principles of biophysical chemistry (pH, buffer, reaction kinetics,
thermodynamics, colligative properties): 72 – 88
E: Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction,
group transfer, biological energy transducers: 89 – 109
F: Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation,
mechanism of enzyme catalysis, isozymes: 110 – 120
G: Conformation of proteins (Ramachandran plot, secondary structure, domains, motif and folds): 121 – 133
H: Conformation of nucleic acids [helix (A, B, Z), t-RNA, micro-RNA] 134 – 136
I: Stability of proteins and nucleic acids: 137 – 138
J: Metabolism of carbohydrates, lipids, amino acids nucleotides and vitamins: 139 - 175

UNIT II: UCELLULAR ORGANIZATION: 176- 285
A: Membrane structure and function (Structure of model membrane, lipid bilayer
and membrane protein diffusion, osmosis, ion channels, active transport,
membrane pumps, mechanism of sorting and regulation of intracellular transport,
electrical properties of membranes): 176 - 199
B: Structural organization and function of intracellular organelles
(Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, endoplasmic reticulum, peroxisomes, plastids, vacuoles, chloroplast, structure & function of cytoskeleton and its role in motility): 200 - 228
C: Organization of genes and chromosomes (Operon, unique and repetitive DNA, interrupted genes, gene families, a structure of chromatin and chromosomes, heterochromatin, euchromatin, transposons): 229-255
D: Cell division and cell cycle (Mitosis and meiosis, their regulation,
steps in the cell cycle, regulation, and control of cell cycle): 256-264
E: Microbial Physiology (Growth yield and characteristics, strategies of cell division, stress response): 265-285

UNIT - III: FUNDAMENTAL PROCESSES: 286-388
A: DNA replication, repair, and recombination (Unit of replication, enzymes
involved, replication origin and replication fork, fidelity of replication,
extrachromosomal replicons, DNA damage and repair mechanisms, homologous
and site-specific recombination): 286-317
B: RNA synthesis and processing (transcription factors and machinery, a formation of initiation complex, transcription activator and repressor, RNA polymerases, capping, elongation, and termination, RNA processing, RNA editing, splicing, and polyadenylation, structure and function of different types of RNA, RNA transport): 318-340
C: Protein synthesis and processing (Ribosome, a formation of initiation complex, initiation factors and their regulation, elongation and elongation factors, termination, the genetic code, aminoacylation of tRNA, tRNA-identity, aminoacyl tRNA synthetase, and translational proof-reading, translational inhibitors, Post- translational modification of proteins): 341-364
D: Control of gene expression at transcription and translation level
(regulating the expression of phages, viruses, prokaryotic and eukaryotic genes, the role of chromatin in gene expression and gene silencing): 365-388